Cochrane Covid-19 update and resources

Cochrane contributors around the world continue to focus on understanding, treating and preventing COVID-19. Cochrane Australia is playing an active role in the National COVID-19 Clinical Evidence Taskforce and continues to collaborate in international efforts to understand, contain and stop the spread of coronavirus.

Here’s a snapshot of this global work to date, along with helpful resources and initiatives now underway.

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Cochrane Library editorials:

• Contested effects and chaotic policies: the 2020 story of (hydroxy) chloroquine for treating Covid‐19

• Covid‐19: working together and making a difference for decision‐makers

• Policy makers must act on incomplete evidence in responding to Covid‐19

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Cochrane Covid-19 Special Collections:

• Coronavirus (Covid-19): evidence relevant to clinical rehabilitation -rehabilitation of individuals who have experienced Covid-19 must consider not only the consequences of the disease but also the effects of treatments applied during the acute phase.

• Effective options for quitting smoking during the pandemic - evidence to support people trying to stop smoking during the Covid-19 pandemic.

• Evidence relevant to critical care - includes reviews identified relevant to the management of people hospitalised with severe acute respiratory infections.

• Infection control and prevention measures - includes reviews directly relevant to the prevention of infection.

• Optimising health in the home workspace - includes reviews focused on helping people stay healthy and well when they work from home.

• Regional anaesthesia to reduce drug use in anaesthesia and avoid aerosol generation - includes reviews directly relevant to support decision-making when planning regional anaesthesia.

• Remote care through telehealth - includes reviews that address using telehealth to support clinical management of conditions including asthma, diabetes, cardiovascular disease, dementia, reproductive health and skin cancer.

• Special Collection on optimising health in the home workspace - includes reviews focused on helping people stay healthy and well when they work from home.

• Support for wellbeing in the healthcare workforce - brings together evidence on interventions that may help support the wellbeing of the healthcare workforce and reduce occupational stress.

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Cochrane reviews & rapid reviews:

• Antibiotics for the treatment of Covid-19

• Antibody tests for identification of current and past infection with SARS‐CoV‐2

• Barriers and facilitators to healthcare workers’ adherence with infection prevention and control (IPC) guidelines for respiratory infectious diseases

• Can non-pharmacological measures prevent or reduce Covid-19 infections in long term care facilities?

• Digital contact tracing technologies in epidemics: a rapid review

• Hand cleaning with ash for reducing the spread of viral and bacterial infections

• Interventions available during pandemics for heavy menstrual bleeding: an overview of Cochrane Reviews

• Interventions to support the resilience and mental health of frontline health and social care professionals during and after a disease outbreak, epidemic or pandemic

• Is vitamin D an effective and safe treatment for COVID-19?

• Ivermectin for preventing and treating COVID-19

• Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome

• Plasma from people who have recovered from Covid-19 to treat individuals with Covid-19

• Personal protective equipment for preventing highlighly infectious diseases due to exposure to contaminated body fluids in health care staff

• Physical interventions to interrupt or reduce the spread of respiratory viruses

• Psychological interventions to foster resilience in healthcare professionals

• Quarantine alone or in combination with other public health measures to control COVID‐19: a rapid review

• Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection

• Remdesivir for the treatment of Covid-10

• Routine laboratory testing to determine if a patient has COVID-19

• Universal screening for people with COVID-19

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Additional resources:

• Care of pregnant women and their babies - Cochrane Pregnancy and Childbirt identify, collate and summarise national clinical practice guideline recommendations for key clinical questions.

• Cochrane Clinical Answers related to Covid-19 - clinically-focused, actionable answers to inform point-of-care decision-making for health professionals.

• Communicating to the public about vaccines and using digital strategies to promote vaccine uptake: information for planners and implementers - based on evidence from systematic reviews, Cochrane Effective Practice and Organisation of Care (EPOC) has prepared three information leaflets for health systems planners and implementers involved in developing vaccine communication strategies.

• Contraception and abortion - resources, guidance and advice statements from international organisations and societies.

• Covid-19 living evidence project - information on Covid-19 trials and synthesized results, frequently updated by independent researchers with expertise in evidence synthesis.

• Dermatology - guidelines, evidence-based resources, and relevant patient information.

• ENT, Hearing and Balance - resources, guidance and advice statements from international organisations and societies.

• Fertility, and pregnancy - resources, guidance, and advice statements from international organisations and societies. Cochrane Gynaecology and Fertility is also maintaining a spreadsheet of published data on pregnancy and neonatal outcomes.

• Global ageing - guidelines and evidence relating to Covid-19 and older people.

• Gynaecological cancers or neuro-oncology - resources, guidance, and advice statements from international organisations and societies.

• Oral and dental care - relevant evidence, resources, guidance and advice statements from international organisations and societies.

• Rehabilitation's REH-COVER project- research focused on fundamental topics related to rehabilitation needs due to Covid-19.

• US COVID-19 Repository - research, resources and reports on Covid-19 and various medical and public health topics.

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Initiatives currently underway:

• Cochrane Covid Review response - includes details on prioritising research questions and methods guidance.

• COVID Reviews database - view and search questions and information on reviews underway.

• Covid-19 Study Register - a one-stop shop for primary research studies related to Covid-19.

• Covid-19 living evidence project - information on Covid trials and synthesized results.

• Health care worker compliance to infection prevention and control guidance - evidence summary by Cochrane Effective Practice and Organizational of Care that looks at implementation considerations.

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For more information and regular updates visit cochrane.org.